Chronic brucellosis with hepatic brucelloma and AA amyloidosis in a patient with autosomal dominant polycystic kidney disease
ABSTRACT We describe an autopsy case of a 45-year-old male diagnosed with autosomal dominant polycystic kidney disease who presented with complaints of altered sensorium. The autopsy revealed multiple tumor-like masses in the liver, which on histological examination depicted multiple large suppurative granulomas with the presence of variable acid-fast coccobacilli (consistent with Brucella spp.). Interestingly, extensive amyloid deposition in multiple organs was noted. To the best of our knowledge, this is the first case of chronic brucellosis causing tumor-like abscesses in the liver accompanied by secondary systemic amyloidosis in a patient with underlying autosomal dominant polycystic kidney disease.
Saved in:
| Main Authors: | , , , , , , |
|---|---|
| Format: | Digital revista |
| Language: | English |
| Published: |
Hospital Universitário da Universidade de São Paulo
2020
|
| Online Access: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S2236-19602020000100300 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| id |
oai:scielo:S2236-19602020000100300 |
|---|---|
| record_format |
ojs |
| spelling |
oai:scielo:S2236-196020200001003002020-10-19Chronic brucellosis with hepatic brucelloma and AA amyloidosis in a patient with autosomal dominant polycystic kidney diseaseKollabathula,ArpithaVishwajeet,VikarnGupta,KirtiMitra,SuvradeepSharma,VibhavRay,PallabBhalla,Ashish Brucellosis Amyloidosis Autopsy Polycystic Kidney, Autosomal Dominant ABSTRACT We describe an autopsy case of a 45-year-old male diagnosed with autosomal dominant polycystic kidney disease who presented with complaints of altered sensorium. The autopsy revealed multiple tumor-like masses in the liver, which on histological examination depicted multiple large suppurative granulomas with the presence of variable acid-fast coccobacilli (consistent with Brucella spp.). Interestingly, extensive amyloid deposition in multiple organs was noted. To the best of our knowledge, this is the first case of chronic brucellosis causing tumor-like abscesses in the liver accompanied by secondary systemic amyloidosis in a patient with underlying autosomal dominant polycystic kidney disease.info:eu-repo/semantics/openAccessHospital Universitário da Universidade de São PauloAutopsy and Case Reports v.10 n.1 20202020-01-01info:eu-repo/semantics/reporttext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S2236-19602020000100300en10.4322/acr.2019.128 |
| institution |
SCIELO |
| collection |
OJS |
| country |
Brasil |
| countrycode |
BR |
| component |
Revista |
| access |
En linea |
| databasecode |
rev-scielo-br |
| tag |
revista |
| region |
America del Sur |
| libraryname |
SciELO |
| language |
English |
| format |
Digital |
| author |
Kollabathula,Arpitha Vishwajeet,Vikarn Gupta,Kirti Mitra,Suvradeep Sharma,Vibhav Ray,Pallab Bhalla,Ashish |
| spellingShingle |
Kollabathula,Arpitha Vishwajeet,Vikarn Gupta,Kirti Mitra,Suvradeep Sharma,Vibhav Ray,Pallab Bhalla,Ashish Chronic brucellosis with hepatic brucelloma and AA amyloidosis in a patient with autosomal dominant polycystic kidney disease |
| author_facet |
Kollabathula,Arpitha Vishwajeet,Vikarn Gupta,Kirti Mitra,Suvradeep Sharma,Vibhav Ray,Pallab Bhalla,Ashish |
| author_sort |
Kollabathula,Arpitha |
| title |
Chronic brucellosis with hepatic brucelloma and AA amyloidosis in a patient with autosomal dominant polycystic kidney disease |
| title_short |
Chronic brucellosis with hepatic brucelloma and AA amyloidosis in a patient with autosomal dominant polycystic kidney disease |
| title_full |
Chronic brucellosis with hepatic brucelloma and AA amyloidosis in a patient with autosomal dominant polycystic kidney disease |
| title_fullStr |
Chronic brucellosis with hepatic brucelloma and AA amyloidosis in a patient with autosomal dominant polycystic kidney disease |
| title_full_unstemmed |
Chronic brucellosis with hepatic brucelloma and AA amyloidosis in a patient with autosomal dominant polycystic kidney disease |
| title_sort |
chronic brucellosis with hepatic brucelloma and aa amyloidosis in a patient with autosomal dominant polycystic kidney disease |
| description |
ABSTRACT We describe an autopsy case of a 45-year-old male diagnosed with autosomal dominant polycystic kidney disease who presented with complaints of altered sensorium. The autopsy revealed multiple tumor-like masses in the liver, which on histological examination depicted multiple large suppurative granulomas with the presence of variable acid-fast coccobacilli (consistent with Brucella spp.). Interestingly, extensive amyloid deposition in multiple organs was noted. To the best of our knowledge, this is the first case of chronic brucellosis causing tumor-like abscesses in the liver accompanied by secondary systemic amyloidosis in a patient with underlying autosomal dominant polycystic kidney disease. |
| publisher |
Hospital Universitário da Universidade de São Paulo |
| publishDate |
2020 |
| url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S2236-19602020000100300 |
| work_keys_str_mv |
AT kollabathulaarpitha chronicbrucellosiswithhepaticbrucellomaandaaamyloidosisinapatientwithautosomaldominantpolycystickidneydisease AT vishwajeetvikarn chronicbrucellosiswithhepaticbrucellomaandaaamyloidosisinapatientwithautosomaldominantpolycystickidneydisease AT guptakirti chronicbrucellosiswithhepaticbrucellomaandaaamyloidosisinapatientwithautosomaldominantpolycystickidneydisease AT mitrasuvradeep chronicbrucellosiswithhepaticbrucellomaandaaamyloidosisinapatientwithautosomaldominantpolycystickidneydisease AT sharmavibhav chronicbrucellosiswithhepaticbrucellomaandaaamyloidosisinapatientwithautosomaldominantpolycystickidneydisease AT raypallab chronicbrucellosiswithhepaticbrucellomaandaaamyloidosisinapatientwithautosomaldominantpolycystickidneydisease AT bhallaashish chronicbrucellosiswithhepaticbrucellomaandaaamyloidosisinapatientwithautosomaldominantpolycystickidneydisease |
| _version_ |
1756439701466644480 |