Chronic brucellosis with hepatic brucelloma and AA amyloidosis in a patient with autosomal dominant polycystic kidney disease

ABSTRACT We describe an autopsy case of a 45-year-old male diagnosed with autosomal dominant polycystic kidney disease who presented with complaints of altered sensorium. The autopsy revealed multiple tumor-like masses in the liver, which on histological examination depicted multiple large suppurative granulomas with the presence of variable acid-fast coccobacilli (consistent with Brucella spp.). Interestingly, extensive amyloid deposition in multiple organs was noted. To the best of our knowledge, this is the first case of chronic brucellosis causing tumor-like abscesses in the liver accompanied by secondary systemic amyloidosis in a patient with underlying autosomal dominant polycystic kidney disease.

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Bibliographic Details
Main Authors: Kollabathula,Arpitha, Vishwajeet,Vikarn, Gupta,Kirti, Mitra,Suvradeep, Sharma,Vibhav, Ray,Pallab, Bhalla,Ashish
Format: Digital revista
Language:English
Published: Hospital Universitário da Universidade de São Paulo 2020
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S2236-19602020000100300
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