Bipolar disorder, a precursor of Parkinson's disease?

ABSTRACT Parkinson's disease is a neurodegenerative disorder predominantly resulting from dopamine depletion in the substantia nigra pars compacta. Some psychiatric disorders may have dopaminergic dysfunction as their substrate. We describe a well-documented case of Parkinson's disease associated with Bipolar Disorder. Although there is some knowledge about the association between these diseases, little is known about its pathophysiology and correlation. We believe that among various hypotheses, many neurotransmitters are linked to this pathophysiology.

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Bibliographic Details
Main Authors: Novaretti,Tânia M.S., Novaretti,Nathália, Tumas,Vitor
Format: Digital revista
Language:English
Published: Academia Brasileira de Neurologia, Departamento de Neurologia Cognitiva e Envelhecimento 2016
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1980-57642016000400361
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