Neutrophil-to-lymphocyte ratio and in-hospital mortality in patients with acute heart failure
OBJECTIVES: Previous studies have demonstrated the role of inflammation in acute heart failure. The neutrophil-to-lymphocyte ratio was found to be a useful inflammatory marker for predicting adverse outcomes. We hypothesized that an elevated neutrophil-to-lymphocyte ratio would be associated with increased mortality in acute heart failure patients. METHODS: The study cohort consisted of 167 acute heart failure patients with an ejection fraction <50%. The primary endpoint was in-hospital mortality, and the patients were divided into two groups according to in-hospital mortality. RESULTS: In a multivariate regression analysis, including baseline demographic, clinical, and biochemical covariates, the neutrophil to lymphocyte ratio remained an independent predictor of mortality (OR 1.156, 95% CI 1.001 - 1.334, p= 0.048). CONCLUSION: In conclusion, an elevated neutrophil-to-lymphocyte ratio seems to be a predictor of short-term mortality in patients with acute heart failure and a reduced left ventricular ejection fraction.
Principais autores: | , , , , , , , , |
---|---|
Formato: | Digital revista |
Idioma: | English |
Publicado em: |
Faculdade de Medicina / USP
2014
|
Acesso em linha: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1807-59322014000300190 |
Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|
id |
oai:scielo:S1807-59322014000300190 |
---|---|
record_format |
ojs |
spelling |
oai:scielo:S1807-593220140003001902015-11-26Neutrophil-to-lymphocyte ratio and in-hospital mortality in patients with acute heart failureTurfan,MuratErdoĞan,ErcanTasal,AbdurrahmanVatankulu,Mehmet AkifJafarov,ParvizSönmez,OsmanErtaş,GökhanBacaksız,AhmetGöktekin,Ömer Neutrophil-to-Lymphocyte Ratio Mortality Acute Heart Failure OBJECTIVES: Previous studies have demonstrated the role of inflammation in acute heart failure. The neutrophil-to-lymphocyte ratio was found to be a useful inflammatory marker for predicting adverse outcomes. We hypothesized that an elevated neutrophil-to-lymphocyte ratio would be associated with increased mortality in acute heart failure patients. METHODS: The study cohort consisted of 167 acute heart failure patients with an ejection fraction <50%. The primary endpoint was in-hospital mortality, and the patients were divided into two groups according to in-hospital mortality. RESULTS: In a multivariate regression analysis, including baseline demographic, clinical, and biochemical covariates, the neutrophil to lymphocyte ratio remained an independent predictor of mortality (OR 1.156, 95% CI 1.001 - 1.334, p= 0.048). CONCLUSION: In conclusion, an elevated neutrophil-to-lymphocyte ratio seems to be a predictor of short-term mortality in patients with acute heart failure and a reduced left ventricular ejection fraction.info:eu-repo/semantics/openAccessFaculdade de Medicina / USPClinics v.69 n.3 20142014-03-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1807-59322014000300190en10.6061/clinics/2014(03)08 |
institution |
SCIELO |
collection |
OJS |
country |
Brasil |
countrycode |
BR |
component |
Revista |
access |
En linea |
databasecode |
rev-scielo-br |
tag |
revista |
region |
America del Sur |
libraryname |
SciELO |
language |
English |
format |
Digital |
author |
Turfan,Murat ErdoĞan,Ercan Tasal,Abdurrahman Vatankulu,Mehmet Akif Jafarov,Parviz Sönmez,Osman Ertaş,Gökhan Bacaksız,Ahmet Göktekin,Ömer |
spellingShingle |
Turfan,Murat ErdoĞan,Ercan Tasal,Abdurrahman Vatankulu,Mehmet Akif Jafarov,Parviz Sönmez,Osman Ertaş,Gökhan Bacaksız,Ahmet Göktekin,Ömer Neutrophil-to-lymphocyte ratio and in-hospital mortality in patients with acute heart failure |
author_facet |
Turfan,Murat ErdoĞan,Ercan Tasal,Abdurrahman Vatankulu,Mehmet Akif Jafarov,Parviz Sönmez,Osman Ertaş,Gökhan Bacaksız,Ahmet Göktekin,Ömer |
author_sort |
Turfan,Murat |
title |
Neutrophil-to-lymphocyte ratio and in-hospital mortality in patients with acute heart failure |
title_short |
Neutrophil-to-lymphocyte ratio and in-hospital mortality in patients with acute heart failure |
title_full |
Neutrophil-to-lymphocyte ratio and in-hospital mortality in patients with acute heart failure |
title_fullStr |
Neutrophil-to-lymphocyte ratio and in-hospital mortality in patients with acute heart failure |
title_full_unstemmed |
Neutrophil-to-lymphocyte ratio and in-hospital mortality in patients with acute heart failure |
title_sort |
neutrophil-to-lymphocyte ratio and in-hospital mortality in patients with acute heart failure |
description |
OBJECTIVES: Previous studies have demonstrated the role of inflammation in acute heart failure. The neutrophil-to-lymphocyte ratio was found to be a useful inflammatory marker for predicting adverse outcomes. We hypothesized that an elevated neutrophil-to-lymphocyte ratio would be associated with increased mortality in acute heart failure patients. METHODS: The study cohort consisted of 167 acute heart failure patients with an ejection fraction <50%. The primary endpoint was in-hospital mortality, and the patients were divided into two groups according to in-hospital mortality. RESULTS: In a multivariate regression analysis, including baseline demographic, clinical, and biochemical covariates, the neutrophil to lymphocyte ratio remained an independent predictor of mortality (OR 1.156, 95% CI 1.001 - 1.334, p= 0.048). CONCLUSION: In conclusion, an elevated neutrophil-to-lymphocyte ratio seems to be a predictor of short-term mortality in patients with acute heart failure and a reduced left ventricular ejection fraction. |
publisher |
Faculdade de Medicina / USP |
publishDate |
2014 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1807-59322014000300190 |
work_keys_str_mv |
AT turfanmurat neutrophiltolymphocyteratioandinhospitalmortalityinpatientswithacuteheartfailure AT erdoganercan neutrophiltolymphocyteratioandinhospitalmortalityinpatientswithacuteheartfailure AT tasalabdurrahman neutrophiltolymphocyteratioandinhospitalmortalityinpatientswithacuteheartfailure AT vatankulumehmetakif neutrophiltolymphocyteratioandinhospitalmortalityinpatientswithacuteheartfailure AT jafarovparviz neutrophiltolymphocyteratioandinhospitalmortalityinpatientswithacuteheartfailure AT sonmezosman neutrophiltolymphocyteratioandinhospitalmortalityinpatientswithacuteheartfailure AT ertasgokhan neutrophiltolymphocyteratioandinhospitalmortalityinpatientswithacuteheartfailure AT bacaksızahmet neutrophiltolymphocyteratioandinhospitalmortalityinpatientswithacuteheartfailure AT goktekinomer neutrophiltolymphocyteratioandinhospitalmortalityinpatientswithacuteheartfailure |
_version_ |
1756432231153270784 |