Neutrophil-to-lymphocyte ratio and in-hospital mortality in patients with acute heart failure

OBJECTIVES: Previous studies have demonstrated the role of inflammation in acute heart failure. The neutrophil-to-lymphocyte ratio was found to be a useful inflammatory marker for predicting adverse outcomes. We hypothesized that an elevated neutrophil-to-lymphocyte ratio would be associated with increased mortality in acute heart failure patients. METHODS: The study cohort consisted of 167 acute heart failure patients with an ejection fraction <50%. The primary endpoint was in-hospital mortality, and the patients were divided into two groups according to in-hospital mortality. RESULTS: In a multivariate regression analysis, including baseline demographic, clinical, and biochemical covariates, the neutrophil to lymphocyte ratio remained an independent predictor of mortality (OR 1.156, 95% CI 1.001 - 1.334, p= 0.048). CONCLUSION: In conclusion, an elevated neutrophil-to-lymphocyte ratio seems to be a predictor of short-term mortality in patients with acute heart failure and a reduced left ventricular ejection fraction.

Bibliographic Details

Main Authors:	Turfan,Murat, ErdoĞan,Ercan, Tasal,Abdurrahman, Vatankulu,Mehmet Akif, Jafarov,Parviz, Sönmez,Osman, Ertaş,Gökhan, Bacaksız,Ahmet, Göktekin,Ömer
Format:	Digital revista
Language:	English
Published:	Faculdade de Medicina / USP 2014
Online Access:	http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1807-59322014000300190
Tags:	Add Tag No Tags, Be the first to tag this record!