Vitamin D: association with eosinophil counts and IgE levels in children with asthma

ABSTRACT In this cross-sectional study, we investigated the relationship that levels of vitamin D had with eosinophil counts and IgE levels in 26 children with asthma (6-12 years of age) in the city of Londrina, Brazil. Vitamin D levels were found to correlate significantly, albeit moderately, with age (r = −0.51) and eosinophilia (r = −0.49), although not with IgE levels (r = −0.12). When we stratified the sample into two groups by the median vitamin D level (< or ≥ 24 ng/mL), we found that those in the < 24 ng/mL group were older, had higher eosinophil counts, and had higher IgE levels. To our knowledge, this is the first study to show an association between low levels of vitamin D and more pronounced eosinophilia in children with asthma in Brazil.

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Autores principales: Amorim,Claudio Luiz Castro Gomes de, Oliveira,Joice Mara de, Rodrigues,Antenor, Furlanetto,Karina Couto, Pitta,Fabio
Formato: Digital revista
Idioma:English
Publicado: Sociedade Brasileira de Pneumologia e Tisiologia 2021
Acceso en línea:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1806-37132021000100300
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