Analysis of bioactive glasses obtained by sol-gel processing for radioactive implants

This paper presents the chemical and physical characterizations of SiO2 and SiO2-CaO bioactive glasses incorporated with samarium atoms, produced by sol-gel synthesis. The objective is to provide biocompatible and biodegradable radioactive seeds as an alternative to be used in Brachytherapy for the treatment of prostate cancer. The glasses were produced and analyzed by X-ray fluorescence spectroscopy (XRF), energy dispersive X-ray spectroscopy (EDS), scanning electron microscopy (SEM), He picnometry and nitrogen adsorption analysis. A theoretical evaluation of the specific activity of the samples upon neutron activation is proposed. The XRF and EDS results demonstrate the incorporation of samarium atoms in the glass matrix. The experimental data coupled with the theoretical studies in neutron activation suggest that it is possible to obtain radioactive seeds with activities equivalent to 125I seeds used in brachytherapy prostatic.

Bibliographic Details

Main Authors:	Roberto,Wanderley dos Santos, Pereira,Marivalda Magalhães, Campos,Tarcísio Passos Ribeiro de
Format:	Digital revista
Language:	English
Published:	ABM, ABC, ABPol 2003
Online Access:	http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-14392003000200003
Tags:	Add Tag No Tags, Be the first to tag this record!