Noncompliance with tuberculosis treatment by patients at a tuberculosis and AIDS reference hospital in midwestern Brazil
Introduction: In developing countries, there is little information about the risk factors that predict noncompliance with tuberculosis (TB) treatment in hospitals. Objective: This study analyzes possible factors associated with noncompliance with TB treatment among patients treated at HAA. Design: A retrospective cohort study was made including all patients who initiated TB treatment at HAA, from January to December 1998. A standard form was used to review medical records and to collect data on each patient. This data was evaluated in comparison with data from the state TB control program. Results: Of the 341 patients included in the study, 186 (61.2%) were considered cured and 67 (22%) were non-compliant. The factors associated with noncompliance were: previous anti-TB treatment (RR = 1.95, 95% CI 1.29 to 2.93), prescription of drugs other than the standard first-line regimen proposed by the Brazilian Health Ministry (Rifampin + Isoniazide + Pyrazinamide) (RR = 0.54, 95% CI 0.35 to 0.83), the need for hospitalization (RR = 2.19, 95% CI 1.46 to 3.29) and non-inclusion in the hospital's TB Control Program for treatment follow up (RR = 0.54, 95% CI 0.35 to 0.82). Setting: Anuar Auad Hospital (HAA) - Goiânia, Goiás, Brazil. Conclusion: Our results indicate the importance of establishing Tuberculosis Control Programs in hospitals, while paying special attention to patients with risk factors for noncompliance with TB treatment.
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Brazilian Society of Infectious Diseases
2002
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oai:scielo:S1413-867020020002000022003-03-25Noncompliance with tuberculosis treatment by patients at a tuberculosis and AIDS reference hospital in midwestern BrazilRabahi,Marcelo FouadRodrigues,Adriana BatistaMello,Fernanda Queiroz deAlmeida Netto,Joaquim Caetano deKritski,Afrânio Lineu Tuberculosis treatment compliance TB control program Goiânia Introduction: In developing countries, there is little information about the risk factors that predict noncompliance with tuberculosis (TB) treatment in hospitals. Objective: This study analyzes possible factors associated with noncompliance with TB treatment among patients treated at HAA. Design: A retrospective cohort study was made including all patients who initiated TB treatment at HAA, from January to December 1998. A standard form was used to review medical records and to collect data on each patient. This data was evaluated in comparison with data from the state TB control program. Results: Of the 341 patients included in the study, 186 (61.2%) were considered cured and 67 (22%) were non-compliant. The factors associated with noncompliance were: previous anti-TB treatment (RR = 1.95, 95% CI 1.29 to 2.93), prescription of drugs other than the standard first-line regimen proposed by the Brazilian Health Ministry (Rifampin + Isoniazide + Pyrazinamide) (RR = 0.54, 95% CI 0.35 to 0.83), the need for hospitalization (RR = 2.19, 95% CI 1.46 to 3.29) and non-inclusion in the hospital's TB Control Program for treatment follow up (RR = 0.54, 95% CI 0.35 to 0.82). Setting: Anuar Auad Hospital (HAA) - Goiânia, Goiás, Brazil. Conclusion: Our results indicate the importance of establishing Tuberculosis Control Programs in hospitals, while paying special attention to patients with risk factors for noncompliance with TB treatment.info:eu-repo/semantics/openAccessBrazilian Society of Infectious DiseasesBrazilian Journal of Infectious Diseases v.6 n.2 20022002-04-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702002000200002en10.1590/S1413-86702002000200002 |
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Rabahi,Marcelo Fouad Rodrigues,Adriana Batista Mello,Fernanda Queiroz de Almeida Netto,Joaquim Caetano de Kritski,Afrânio Lineu |
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Rabahi,Marcelo Fouad Rodrigues,Adriana Batista Mello,Fernanda Queiroz de Almeida Netto,Joaquim Caetano de Kritski,Afrânio Lineu Noncompliance with tuberculosis treatment by patients at a tuberculosis and AIDS reference hospital in midwestern Brazil |
author_facet |
Rabahi,Marcelo Fouad Rodrigues,Adriana Batista Mello,Fernanda Queiroz de Almeida Netto,Joaquim Caetano de Kritski,Afrânio Lineu |
author_sort |
Rabahi,Marcelo Fouad |
title |
Noncompliance with tuberculosis treatment by patients at a tuberculosis and AIDS reference hospital in midwestern Brazil |
title_short |
Noncompliance with tuberculosis treatment by patients at a tuberculosis and AIDS reference hospital in midwestern Brazil |
title_full |
Noncompliance with tuberculosis treatment by patients at a tuberculosis and AIDS reference hospital in midwestern Brazil |
title_fullStr |
Noncompliance with tuberculosis treatment by patients at a tuberculosis and AIDS reference hospital in midwestern Brazil |
title_full_unstemmed |
Noncompliance with tuberculosis treatment by patients at a tuberculosis and AIDS reference hospital in midwestern Brazil |
title_sort |
noncompliance with tuberculosis treatment by patients at a tuberculosis and aids reference hospital in midwestern brazil |
description |
Introduction: In developing countries, there is little information about the risk factors that predict noncompliance with tuberculosis (TB) treatment in hospitals. Objective: This study analyzes possible factors associated with noncompliance with TB treatment among patients treated at HAA. Design: A retrospective cohort study was made including all patients who initiated TB treatment at HAA, from January to December 1998. A standard form was used to review medical records and to collect data on each patient. This data was evaluated in comparison with data from the state TB control program. Results: Of the 341 patients included in the study, 186 (61.2%) were considered cured and 67 (22%) were non-compliant. The factors associated with noncompliance were: previous anti-TB treatment (RR = 1.95, 95% CI 1.29 to 2.93), prescription of drugs other than the standard first-line regimen proposed by the Brazilian Health Ministry (Rifampin + Isoniazide + Pyrazinamide) (RR = 0.54, 95% CI 0.35 to 0.83), the need for hospitalization (RR = 2.19, 95% CI 1.46 to 3.29) and non-inclusion in the hospital's TB Control Program for treatment follow up (RR = 0.54, 95% CI 0.35 to 0.82). Setting: Anuar Auad Hospital (HAA) - Goiânia, Goiás, Brazil. Conclusion: Our results indicate the importance of establishing Tuberculosis Control Programs in hospitals, while paying special attention to patients with risk factors for noncompliance with TB treatment. |
publisher |
Brazilian Society of Infectious Diseases |
publishDate |
2002 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702002000200002 |
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