Evaluation of the effect of hospitalization on mortality in patients with heart failure followed in primary care

Abstract Background: Heart failure (HF) is a serious health-care problem. The aim of this study is to evaluate the effect of the first acute episode of decompensated HF that requires a hospitalization on the survival of newly diagnosed cases of HF with follow-up for 5 years in primary care (PC). Methods: This was a longitudinal observational study of a retrospective cohort of patients with information extracted from electronic medical records of PC. Incident cases of HF from 2006 to 2010 or until death were studied through a survival analysis with Kaplan–Meier and Cox proportional hazards multivariate regression, after applying the propensity score matching technique (PSM). Results: A total of 3061 new cases of HF were identified. The PSM analysis was performed with 529 couples, with a total of 1058 patients. 5-year survival was 65% in no hospitalized and 53% in hospitalized patients. Factors with an increased risk of mortality were having prescribed nitrates (heart rate [HR] = 1.56; 1.08-2.24). Factors with protective effect were having received the annual influenza vaccine (HR = 0.04; 0.01-0.15) and having been indicated X-rays by PC physician (HR = 0.76; 0.67-0.88). Conclusions: The findings indicate that hospitalizations are associated with a significant increase in mortality in patients recently diagnosed with HF. It is important to reinforce the need for the prevention of acute decompensated HF and for strategies to improve post-discharge outcomes.

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Bibliographic Details
Main Authors: Prado-Galbarro,Francisco J., Gamiño-Arroyo,Ana E., Sánchez-Piedra,Carlos, Sánchez-Pájaro,Andrés, Sarría-Santamera,Antonio
Format: Digital revista
Language:English
Published: Instituto Nacional de Cardiología Ignacio Chávez 2019
Online Access:http://www.scielo.org.mx/scielo.php?script=sci_arttext&pid=S1405-99402019000200130
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