ANTIBACTERIAL AND ANTIFUNGAL TERPENES FROM Pilgerodendron uviferum (D. DON) FLORIN

Ten sesquiterpenes (a-cubebene, copaene, alpha-caryophyllene, caryophyllene-4,5-epoxide, delta-cadinene, cubenol, epicubenol, torreyol, humulene-1,2-epoxide, 15-copaenol) and six diterpenes (hinokione, hinokiol, ferruginol, 6,7-dehydroferruginol, totarol, sugiol) were isolated and identified from Pilgerodendron uviferum (D. Don) Florin wood and bark. The molecular structures were elucidated by spectroscopic methods. Twelve pure compounds were tested for antimicrobial activity against standard bacterial (Staphylococcus aureus, Bacillus subtilis, Escherichia coli, Pseudomonas aureginosa, Streptococcus pyogenes) and fungal strains (Ophiostoma piliferum, Rhizoctonia solani, Phragmidium violaceum, Fusarium graminearum, Pythium irregulare, Botrytis cinerea, Schizophyllum commune), as were crude total extracts, n-hexane, dichloromethane, and ethyl acetate partial extracts. All the compounds tested exhibited biological activity, with the most active being ferruginol, hinokiol, 15-copaenol, cubenol, torreyol, and n-hexane wood extracts and ethyl acetate bark extract

Bibliographic Details

Main Authors:	Solís,C., Becerra,J., Flores,C., Robledo,J., Silva,M.
Format:	Digital revista
Language:	English
Published:	Sociedad Chilena de Química 2004
Online Access:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072004000200010
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