Lobomycosis: a therapeutic challenge

Abstract: Lobomycosis or lacaziosis is a chronic granulomatous fungal infection caused by Lacazia loboi. Most cases are restricted to tropical regions. Transmission is believed to occur through traumatic inoculation in the skin, mainly in exposed areas. It is characterized by keloid-like nodules. There are only a few hundred cases reported. The differential diagnoses include many skin conditions, and treatment is difficult. The reported case, initially diagnosed as keloid, proved to be refractory to surgical treatment alone. It was subsequently approached with extensive surgery, cryotherapy every three months and a combination of itraconazole and clofazimine for two years. No signs of clinical and histopathological activity were detected during follow-up.

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Bibliographic Details
Main Authors: Araújo,Marcelo Grossi, Cirilo,Nathalie Silva, Santos,Soraya Neves Marques Barbosa dos, Aguilar,Claudemir Roberto, Guedes,Antonio Carlos Martins
Format: Digital revista
Language:English
Published: Sociedade Brasileira de Dermatologia 2018
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962018000200279
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