Linear IgA and IgG bullous dermatosis

Abstract Childhood linear immunoglobulin A dermatosis is a rare autoimmune vesiculobullous disease. It results in linear deposition of autoantibodies (immunoglobulin A) against antigens in the basal membrane zone, leading to subepidermal cleavage. Additional depositions of immunoglobulin G and complement-3 might occur. It is still debated whether concomitant findings of immunoglobulins A and G should be considered a subtype of this dermatosis or a new entity. Further studies are needed to recognize this clinical variant.

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Auteurs principaux: Fernandes,Karina de Almeida Pinto, Galvis,Kely Hernández, Gomes,Anndressa Camillo da Matta Setubal, Nogueira,Osvania Maris, Felix,Paulo Antônio Oldani, Vargas,Thiago Jeunon de Sousa
Format: Digital revista
Langue:English
Publié: Sociedade Brasileira de Dermatologia 2016
Accès en ligne:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962016001100032
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