Cutaneous metastases from gastric adenocarcinoma 15 years after curative gastrectomy

Abstract We report the case of a 38-year-old man, who developed cutaneous metastases in the left inguinal groove 15 years after curative gastrectomy for advanced gastric adenocarcinoma. Histopathologic examination revealed poorly differentiated adenocarcinoma cells. They were stained positive for villin, CDX-2, CKpan (AE1/ AE3), CEA, CK8/18, CK19, CK7, EMA, Ki-67 (50%), and negative for S-100, CK20, CD34, GCDFP-15 and TTF-1. The patient underwent local excision, after the presence of other metastases was excluded. Nevertheless, local recurrence developed at the surgical bed one year later and PET/CT revealed metastases to lymph nodes, bone and skin. He died 2 years after the appearance of cutaneous metastases. We have reviewed the literature and described the immunohistochemical characteristics of cutaneous metastases from gastric adenocarcinoma.

Bibliographic Details

Main Authors:	Liu,Fang, Yan,Wen Liang, Liu,Haibo, Zhang,Min, Sang,Hong
Format:	Digital revista
Language:	English
Published:	Sociedade Brasileira de Dermatologia 2015
Online Access:	http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962015000700046
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