Exuberant clinical picture of Buschke-Fischer-Brauer palmoplantar keratoderma in bedridden patient

Buschke-Fisher-Brauer keratoderma is a rare hereditary autosomal dominant disease of incomplete penetrance. Important differential diagnoses include other palmoplantar keratinization disorders, acquired or hereditary, which is done based on the histopathological findings. This diagnosis alerts especially about the possibility of associated neoplasms. Treatment involves topical keratolytic agents, usually with little efficacy, or with long-term systemic retinoids with follow-up of exuberant collateral effects.

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Bibliographic Details
Main Authors: Antonio,João Roberto, Oliveira,Guilherme Bueno de, Rossi,Natalia Cristina Pires, Pires,Laiza Gabriela Garcia
Format: Digital revista
Language:English
Published: Sociedade Brasileira de Dermatologia 2014
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962014000500819
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