Comparative scanning electron microscopy of bullous diseases

The purpose of this study is to compare scanning electron microscopy findings of the blister roof in three distinct bullous diseases: one intraepidermal acantholytic (pemphigus foliaceus); one due to hemidesmosomal dysfunction (bullous pemphigoid); and one secondary to anchoring fibril dysfunction - type VII collagen (dystrophic epidermolysis bullosa). In pemphigus foliaceus, acantholytic phenomena were readily demonstrated. In bullous pemphigoid, the epidermis had a solid aspect. In dystrophic epidermolysis bullosa a net was seen in the blister roof.

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Bibliographic Details
Main Authors: Almeida Jr,Hiram Larangeira de, Rossi,Gabriela, Karam,Octavio Ruschel, Rocha,Nara Moreira, Silva,Ricardo Marques e
Format: Digital revista
Language:English
Published: Sociedade Brasileira de Dermatologia 2014
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962014000200347
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