Rapidly progressive post-transplant lymphoproliferative disease following withdrawal of sirolimus
Sirolimus, a potent inhibitor of B- and T-cell activation, is a commonly used immunosuppressant after renal transplantation. Withdrawal of sirolimus from the immunosuppression regimen may reduce B-cell surveillance. We present a case of rapidly progressive central nervous system (CNS) polymorphic Epstein-Barr virus (EBV)-related post-transplant lymphoproliferative disorder following the withdrawal of sirolimus
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Main Authors: | , , , , , , |
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Format: | Digital revista |
Language: | English |
Published: |
South African Medical Association
2012
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Online Access: | http://www.scielo.org.za/scielo.php?script=sci_arttext&pid=S0256-95742012001200017 |
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