Rapidly progressive post-transplant lymphoproliferative disease following withdrawal of sirolimus

Sirolimus, a potent inhibitor of B- and T-cell activation, is a commonly used immunosuppressant after renal transplantation. Withdrawal of sirolimus from the immunosuppression regimen may reduce B-cell surveillance. We present a case of rapidly progressive central nervous system (CNS) polymorphic Epstein-Barr virus (EBV)-related post-transplant lymphoproliferative disorder following the withdrawal of sirolimus

Saved in:
Bibliographic Details
Main Authors: Mendelson,M, Barday,Z, Eastman,R, Le Feuvre,D, Candy,S, Wu,H, Swanepoel,C
Format: Digital revista
Language:English
Published: South African Medical Association 2012
Online Access:http://www.scielo.org.za/scielo.php?script=sci_arttext&pid=S0256-95742012001200017
Tags: Add Tag
No Tags, Be the first to tag this record!