Cachexia in hospitalized patients with heart failure
Abstract Aims: to evaluate cachexia prevalence in hospitalized heart failure (HF) patients by comparing two methods for diagnosing cachexia and alterations in each component involved in its diagnosis. Method: a cross-sectional study, involving patients diagnosed with HF and admitted between April and August 2015 to a public hospital in the Brazilian Northeast. Cardiac cachexia was defined using the Cachexia Consensus criteria (Washington, DC), which defines cachexia as ≥ 5% unintentional weight loss in the previous 12 months or a body mass index (BMI) ≤ 20.0 kg/m², in combination with at least two of the following criteria: fatigue, anorexia, low hand grip strength, low muscle strength, and biological alterations (hemoglobin < 12 g/dl, albumin < 3.2 g/dl, and PCR ≥ 5 mg/dl), and for comparative purposes a diagnostic criterion which considers weight loss ≥ 6% in at least six months as a cachexia diagnosis. Results: one hundred and fifty-six individuals were evaluated, with an average age of 59.1 (± 15.3). Cachexia prevalence was 37.2% and associated with a low BMI (p < 0.001), low muscle mass (p < 0.001), reduced ejection fraction (p = 0.005), hypoalbuminemia (p = 0.040), and anemia (p = 0.002). Among the diagnostic components, the greatest alterations were observed in relation to fatigue (88.2%), anorexia (72.1%) and weight loss (61.7%). Conclusions: the high prevalence of diagnosed cachexia indicates that this condition is common and is associated with poor nutritional state and clinical condition.
| Main Authors: | , , , |
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| Format: | Digital revista |
| Language: | English |
| Published: |
Grupo Arán
2018
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| Online Access: | http://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S0212-16112018000300669 |
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