Pharmacological therapy and cardiovascular risk reduction for type 2 diabetes

SUMMARY The pharmacological therapy for type 2 diabetes mellitus has presented important advances in recent years, which has impacted the treatment of patients with established cardiovascular disease or with high cardiovascular risk. In this scenario, two drug classes have emerged and demonstrated clear clinical benefits: SGLT-2 inhibitors and GLP-1 agonists. The present review discusses the pharmacology, adverse effects, and clinical trials that have demonstrated the benefits of these medications in reducing cardiovascular risk.

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Bibliographic Details
Main Authors: Martins,Eduardo Bello, Lima,Eduardo Gomes, Pitta,Fábio Grunspun, Carvalho,Leticia Neves Solon, Queiroz,Thiago Dias de, Serrano Júnior,Carlos Vicente
Format: Digital revista
Language:English
Published: Associação Médica Brasileira 2020
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0104-42302020000901283
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