Vitamin D serum levels and peripheral arterial disease among southern Brazilian adults

SUMMARY OBJECTIVE To investigate the association between low serum vitamin D levels and peripheral arterial disease (PAD). METHODS A cross-sectional study with a consecutive sample of 133 individuals from Caxias do Sul, Brasil. We considered PAD patients those with an ankle-brachial index (ABI) ≤ 0.90 or with arterial revascularization. Vitamin D serum level was categorized as sufficient (≥30 ng/mL), insufficient (>20 to 29 ng/mL), and deficient (<20 ng/mL). Prevalence ratios (RP) were calculated through Poisson regression. RESULTS The prevalence of PAD was 50.7% (95% CI 42-59). After adjustment for potential PAD risk factors, RP were 1.08 (95% CI 0.66-1.76) for insufficient serum level and 1.57 (95% CI 0.96-2.57) for deficient vitamin D serum level; (p for trend = 0.020). CONCLUSION Vitamin D serum levels showed an inverse and significant dose-response relationship with PAD.

Bibliographic Details

Main Authors:	Bonatto,Simone, Paniz,Vera Maria Vieira, Dutra,Clandio de Freitas, Henn,Ruth Liane
Format:	Digital revista
Language:	English
Published:	Associação Médica Brasileira 2020
Online Access:	http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0104-42302020000300268
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