Functional decline in the elderly with MCI: Cultural adaptation of the ADCS-ADL scale

Summary Objective: Translate, transcultural adaptation and application to Brazilian Portuguese of the Alzheimer’s Disease Cooperative Study - Activities of Daily Living (ADCS-ADL) scale as a cognitive screening instrument. Method: We applied the back translation added with pretest and bilingual methods. The sample was composed by 95 elderly individuals and their caregivers. Thirty-two (32) participants were diagnosed as mild cognitive impairment (MCI) patients, 33 as Alzheimer’s disease (AD) patients and 30 were considered as cognitively normal individuals. Results: There were only little changes on the scale. The Cronbach alpha coefficient was 0.89. The scores were 72.9 for control group, followed by MCI (65.1) and by AD (55.9), with a p-value < 0.001. The ROC curve value was 0.89. We considered a cut point of 72 and we observed a sensibility of 86.2%, specificity of 70%, positive predictive value of 86.2%, negative predictive value of 70%, positive likelihood ratio of 2.9 and negative likelihood ratio of 0.2. Conclusion: ADCS-ADL scale presents satisfactory psychometric properties to discriminate between MCI, AD and normal cognition.

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Main Authors: Cintra,Fabiana Carla Matos da Cunha, Cintra,Marco Túlio Gualberto, Nicolato,Rodrigo, Bertola,Laiss, Ávila,Rafaela Teixeira, Malloy-Diniz,Leandro Fernandes, Moraes,Edgar Nunes, Bicalho,Maria Aparecida Camargos
Format: Digital revista
Language:English
Published: Associação Médica Brasileira 2017
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0104-42302017000700590
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spelling oai:scielo:S0104-423020170007005902017-09-25Functional decline in the elderly with MCI: Cultural adaptation of the ADCS-ADL scaleCintra,Fabiana Carla Matos da CunhaCintra,Marco Túlio GualbertoNicolato,RodrigoBertola,LaissÁvila,Rafaela TeixeiraMalloy-Diniz,Leandro FernandesMoraes,Edgar NunesBicalho,Maria Aparecida Camargos mild cognitive impairment Alzheimer’s disease activities of daily living Summary Objective: Translate, transcultural adaptation and application to Brazilian Portuguese of the Alzheimer’s Disease Cooperative Study - Activities of Daily Living (ADCS-ADL) scale as a cognitive screening instrument. Method: We applied the back translation added with pretest and bilingual methods. The sample was composed by 95 elderly individuals and their caregivers. Thirty-two (32) participants were diagnosed as mild cognitive impairment (MCI) patients, 33 as Alzheimer’s disease (AD) patients and 30 were considered as cognitively normal individuals. Results: There were only little changes on the scale. The Cronbach alpha coefficient was 0.89. The scores were 72.9 for control group, followed by MCI (65.1) and by AD (55.9), with a p-value < 0.001. The ROC curve value was 0.89. We considered a cut point of 72 and we observed a sensibility of 86.2%, specificity of 70%, positive predictive value of 86.2%, negative predictive value of 70%, positive likelihood ratio of 2.9 and negative likelihood ratio of 0.2. Conclusion: ADCS-ADL scale presents satisfactory psychometric properties to discriminate between MCI, AD and normal cognition.info:eu-repo/semantics/openAccessAssociação Médica BrasileiraRevista da Associação Médica Brasileira v.63 n.7 20172017-07-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0104-42302017000700590en10.1590/1806-9282.63.07.590
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language English
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author Cintra,Fabiana Carla Matos da Cunha
Cintra,Marco Túlio Gualberto
Nicolato,Rodrigo
Bertola,Laiss
Ávila,Rafaela Teixeira
Malloy-Diniz,Leandro Fernandes
Moraes,Edgar Nunes
Bicalho,Maria Aparecida Camargos
spellingShingle Cintra,Fabiana Carla Matos da Cunha
Cintra,Marco Túlio Gualberto
Nicolato,Rodrigo
Bertola,Laiss
Ávila,Rafaela Teixeira
Malloy-Diniz,Leandro Fernandes
Moraes,Edgar Nunes
Bicalho,Maria Aparecida Camargos
Functional decline in the elderly with MCI: Cultural adaptation of the ADCS-ADL scale
author_facet Cintra,Fabiana Carla Matos da Cunha
Cintra,Marco Túlio Gualberto
Nicolato,Rodrigo
Bertola,Laiss
Ávila,Rafaela Teixeira
Malloy-Diniz,Leandro Fernandes
Moraes,Edgar Nunes
Bicalho,Maria Aparecida Camargos
author_sort Cintra,Fabiana Carla Matos da Cunha
title Functional decline in the elderly with MCI: Cultural adaptation of the ADCS-ADL scale
title_short Functional decline in the elderly with MCI: Cultural adaptation of the ADCS-ADL scale
title_full Functional decline in the elderly with MCI: Cultural adaptation of the ADCS-ADL scale
title_fullStr Functional decline in the elderly with MCI: Cultural adaptation of the ADCS-ADL scale
title_full_unstemmed Functional decline in the elderly with MCI: Cultural adaptation of the ADCS-ADL scale
title_sort functional decline in the elderly with mci: cultural adaptation of the adcs-adl scale
description Summary Objective: Translate, transcultural adaptation and application to Brazilian Portuguese of the Alzheimer’s Disease Cooperative Study - Activities of Daily Living (ADCS-ADL) scale as a cognitive screening instrument. Method: We applied the back translation added with pretest and bilingual methods. The sample was composed by 95 elderly individuals and their caregivers. Thirty-two (32) participants were diagnosed as mild cognitive impairment (MCI) patients, 33 as Alzheimer’s disease (AD) patients and 30 were considered as cognitively normal individuals. Results: There were only little changes on the scale. The Cronbach alpha coefficient was 0.89. The scores were 72.9 for control group, followed by MCI (65.1) and by AD (55.9), with a p-value < 0.001. The ROC curve value was 0.89. We considered a cut point of 72 and we observed a sensibility of 86.2%, specificity of 70%, positive predictive value of 86.2%, negative predictive value of 70%, positive likelihood ratio of 2.9 and negative likelihood ratio of 0.2. Conclusion: ADCS-ADL scale presents satisfactory psychometric properties to discriminate between MCI, AD and normal cognition.
publisher Associação Médica Brasileira
publishDate 2017
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0104-42302017000700590
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