Functional decline in the elderly with MCI: Cultural adaptation of the ADCS-ADL scale

Summary Objective: Translate, transcultural adaptation and application to Brazilian Portuguese of the Alzheimer’s Disease Cooperative Study - Activities of Daily Living (ADCS-ADL) scale as a cognitive screening instrument. Method: We applied the back translation added with pretest and bilingual methods. The sample was composed by 95 elderly individuals and their caregivers. Thirty-two (32) participants were diagnosed as mild cognitive impairment (MCI) patients, 33 as Alzheimer’s disease (AD) patients and 30 were considered as cognitively normal individuals. Results: There were only little changes on the scale. The Cronbach alpha coefficient was 0.89. The scores were 72.9 for control group, followed by MCI (65.1) and by AD (55.9), with a p-value < 0.001. The ROC curve value was 0.89. We considered a cut point of 72 and we observed a sensibility of 86.2%, specificity of 70%, positive predictive value of 86.2%, negative predictive value of 70%, positive likelihood ratio of 2.9 and negative likelihood ratio of 0.2. Conclusion: ADCS-ADL scale presents satisfactory psychometric properties to discriminate between MCI, AD and normal cognition.

Bibliographic Details

Main Authors:	Cintra,Fabiana Carla Matos da Cunha, Cintra,Marco Túlio Gualberto, Nicolato,Rodrigo, Bertola,Laiss, Ávila,Rafaela Teixeira, Malloy-Diniz,Leandro Fernandes, Moraes,Edgar Nunes, Bicalho,Maria Aparecida Camargos
Format:	Digital revista
Language:	English
Published:	Associação Médica Brasileira 2017
Online Access:	http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0104-42302017000700590
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