Clinical profile of patients with myasthenia gravis followed at the University Hospital, Federal University of Minas Gerais

Summary Objective: to determine the clinical profile of patients with myasthenia gravis (MG); followed at the Neuromuscular Diseases Clinic of the University Hospital, Federal University of Minas Gerais, Brazil, and to compare it with other Brazilian case series. Methods: sociodemographic and clinical data were collected from patients, and a systematic literature review performed, focusing on national studies on the clinical profile of MG patients. Results: sixty nine patients were enrolled in the study. Fifty five (91%) subjects were female and the mean age (SD) was 37.6 (±11.4) years. The mean disease duration was 14.1 years. Regarding treatment, prednisone was the most used strategy (64%), followed by the use of azathioprine (43%). There was no difference between thymectomized (42) and non-thymectomized (27) patients regarding disease severity and medication use. Conclusion: clinical and socio-demographic features of this MG sample from a University-based clinic resemble those reported in other Brazilian series and in the international literature.

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Main Authors: Mourão,Aline Mansueto, Barbosa,Luiz Sérgio Mageste, Comini-Frota,Elizabeth Regina, Freitas,Denise da Silva, Gomez,Rodrigo Santiago, Burns,Ted M., Lemos,Stela Maris Aguiar, Teixeira,Antonio Lúcio
Format: Digital revista
Language:English
Published: Associação Médica Brasileira 2015
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0104-42302015000200156
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spelling oai:scielo:S0104-423020150002001562015-07-27Clinical profile of patients with myasthenia gravis followed at the University Hospital, Federal University of Minas GeraisMourão,Aline MansuetoBarbosa,Luiz Sérgio MagesteComini-Frota,Elizabeth ReginaFreitas,Denise da SilvaGomez,Rodrigo SantiagoBurns,Ted M.Lemos,Stela Maris AguiarTeixeira,Antonio Lúcio myasthenia gravis epidemiology neurology thymectomy therapeutics Summary Objective: to determine the clinical profile of patients with myasthenia gravis (MG); followed at the Neuromuscular Diseases Clinic of the University Hospital, Federal University of Minas Gerais, Brazil, and to compare it with other Brazilian case series. Methods: sociodemographic and clinical data were collected from patients, and a systematic literature review performed, focusing on national studies on the clinical profile of MG patients. Results: sixty nine patients were enrolled in the study. Fifty five (91%) subjects were female and the mean age (SD) was 37.6 (±11.4) years. The mean disease duration was 14.1 years. Regarding treatment, prednisone was the most used strategy (64%), followed by the use of azathioprine (43%). There was no difference between thymectomized (42) and non-thymectomized (27) patients regarding disease severity and medication use. Conclusion: clinical and socio-demographic features of this MG sample from a University-based clinic resemble those reported in other Brazilian series and in the international literature. info:eu-repo/semantics/openAccessAssociação Médica BrasileiraRevista da Associação Médica Brasileira v.61 n.2 20152015-04-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0104-42302015000200156en10.1590/1806-9282.61.02.156
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language English
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author Mourão,Aline Mansueto
Barbosa,Luiz Sérgio Mageste
Comini-Frota,Elizabeth Regina
Freitas,Denise da Silva
Gomez,Rodrigo Santiago
Burns,Ted M.
Lemos,Stela Maris Aguiar
Teixeira,Antonio Lúcio
spellingShingle Mourão,Aline Mansueto
Barbosa,Luiz Sérgio Mageste
Comini-Frota,Elizabeth Regina
Freitas,Denise da Silva
Gomez,Rodrigo Santiago
Burns,Ted M.
Lemos,Stela Maris Aguiar
Teixeira,Antonio Lúcio
Clinical profile of patients with myasthenia gravis followed at the University Hospital, Federal University of Minas Gerais
author_facet Mourão,Aline Mansueto
Barbosa,Luiz Sérgio Mageste
Comini-Frota,Elizabeth Regina
Freitas,Denise da Silva
Gomez,Rodrigo Santiago
Burns,Ted M.
Lemos,Stela Maris Aguiar
Teixeira,Antonio Lúcio
author_sort Mourão,Aline Mansueto
title Clinical profile of patients with myasthenia gravis followed at the University Hospital, Federal University of Minas Gerais
title_short Clinical profile of patients with myasthenia gravis followed at the University Hospital, Federal University of Minas Gerais
title_full Clinical profile of patients with myasthenia gravis followed at the University Hospital, Federal University of Minas Gerais
title_fullStr Clinical profile of patients with myasthenia gravis followed at the University Hospital, Federal University of Minas Gerais
title_full_unstemmed Clinical profile of patients with myasthenia gravis followed at the University Hospital, Federal University of Minas Gerais
title_sort clinical profile of patients with myasthenia gravis followed at the university hospital, federal university of minas gerais
description Summary Objective: to determine the clinical profile of patients with myasthenia gravis (MG); followed at the Neuromuscular Diseases Clinic of the University Hospital, Federal University of Minas Gerais, Brazil, and to compare it with other Brazilian case series. Methods: sociodemographic and clinical data were collected from patients, and a systematic literature review performed, focusing on national studies on the clinical profile of MG patients. Results: sixty nine patients were enrolled in the study. Fifty five (91%) subjects were female and the mean age (SD) was 37.6 (±11.4) years. The mean disease duration was 14.1 years. Regarding treatment, prednisone was the most used strategy (64%), followed by the use of azathioprine (43%). There was no difference between thymectomized (42) and non-thymectomized (27) patients regarding disease severity and medication use. Conclusion: clinical and socio-demographic features of this MG sample from a University-based clinic resemble those reported in other Brazilian series and in the international literature.
publisher Associação Médica Brasileira
publishDate 2015
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0104-42302015000200156
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