Clinical profile of patients with myasthenia gravis followed at the University Hospital, Federal University of Minas Gerais
Summary Objective: to determine the clinical profile of patients with myasthenia gravis (MG); followed at the Neuromuscular Diseases Clinic of the University Hospital, Federal University of Minas Gerais, Brazil, and to compare it with other Brazilian case series. Methods: sociodemographic and clinical data were collected from patients, and a systematic literature review performed, focusing on national studies on the clinical profile of MG patients. Results: sixty nine patients were enrolled in the study. Fifty five (91%) subjects were female and the mean age (SD) was 37.6 (±11.4) years. The mean disease duration was 14.1 years. Regarding treatment, prednisone was the most used strategy (64%), followed by the use of azathioprine (43%). There was no difference between thymectomized (42) and non-thymectomized (27) patients regarding disease severity and medication use. Conclusion: clinical and socio-demographic features of this MG sample from a University-based clinic resemble those reported in other Brazilian series and in the international literature.
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Associação Médica Brasileira
2015
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oai:scielo:S0104-423020150002001562015-07-27Clinical profile of patients with myasthenia gravis followed at the University Hospital, Federal University of Minas GeraisMourão,Aline MansuetoBarbosa,Luiz Sérgio MagesteComini-Frota,Elizabeth ReginaFreitas,Denise da SilvaGomez,Rodrigo SantiagoBurns,Ted M.Lemos,Stela Maris AguiarTeixeira,Antonio Lúcio myasthenia gravis epidemiology neurology thymectomy therapeutics Summary Objective: to determine the clinical profile of patients with myasthenia gravis (MG); followed at the Neuromuscular Diseases Clinic of the University Hospital, Federal University of Minas Gerais, Brazil, and to compare it with other Brazilian case series. Methods: sociodemographic and clinical data were collected from patients, and a systematic literature review performed, focusing on national studies on the clinical profile of MG patients. Results: sixty nine patients were enrolled in the study. Fifty five (91%) subjects were female and the mean age (SD) was 37.6 (±11.4) years. The mean disease duration was 14.1 years. Regarding treatment, prednisone was the most used strategy (64%), followed by the use of azathioprine (43%). There was no difference between thymectomized (42) and non-thymectomized (27) patients regarding disease severity and medication use. Conclusion: clinical and socio-demographic features of this MG sample from a University-based clinic resemble those reported in other Brazilian series and in the international literature. info:eu-repo/semantics/openAccessAssociação Médica BrasileiraRevista da Associação Médica Brasileira v.61 n.2 20152015-04-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0104-42302015000200156en10.1590/1806-9282.61.02.156 |
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Mourão,Aline Mansueto Barbosa,Luiz Sérgio Mageste Comini-Frota,Elizabeth Regina Freitas,Denise da Silva Gomez,Rodrigo Santiago Burns,Ted M. Lemos,Stela Maris Aguiar Teixeira,Antonio Lúcio |
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Mourão,Aline Mansueto Barbosa,Luiz Sérgio Mageste Comini-Frota,Elizabeth Regina Freitas,Denise da Silva Gomez,Rodrigo Santiago Burns,Ted M. Lemos,Stela Maris Aguiar Teixeira,Antonio Lúcio Clinical profile of patients with myasthenia gravis followed at the University Hospital, Federal University of Minas Gerais |
author_facet |
Mourão,Aline Mansueto Barbosa,Luiz Sérgio Mageste Comini-Frota,Elizabeth Regina Freitas,Denise da Silva Gomez,Rodrigo Santiago Burns,Ted M. Lemos,Stela Maris Aguiar Teixeira,Antonio Lúcio |
author_sort |
Mourão,Aline Mansueto |
title |
Clinical profile of patients with myasthenia gravis followed at the University Hospital, Federal University of Minas Gerais |
title_short |
Clinical profile of patients with myasthenia gravis followed at the University Hospital, Federal University of Minas Gerais |
title_full |
Clinical profile of patients with myasthenia gravis followed at the University Hospital, Federal University of Minas Gerais |
title_fullStr |
Clinical profile of patients with myasthenia gravis followed at the University Hospital, Federal University of Minas Gerais |
title_full_unstemmed |
Clinical profile of patients with myasthenia gravis followed at the University Hospital, Federal University of Minas Gerais |
title_sort |
clinical profile of patients with myasthenia gravis followed at the university hospital, federal university of minas gerais |
description |
Summary Objective: to determine the clinical profile of patients with myasthenia gravis (MG); followed at the Neuromuscular Diseases Clinic of the University Hospital, Federal University of Minas Gerais, Brazil, and to compare it with other Brazilian case series. Methods: sociodemographic and clinical data were collected from patients, and a systematic literature review performed, focusing on national studies on the clinical profile of MG patients. Results: sixty nine patients were enrolled in the study. Fifty five (91%) subjects were female and the mean age (SD) was 37.6 (±11.4) years. The mean disease duration was 14.1 years. Regarding treatment, prednisone was the most used strategy (64%), followed by the use of azathioprine (43%). There was no difference between thymectomized (42) and non-thymectomized (27) patients regarding disease severity and medication use. Conclusion: clinical and socio-demographic features of this MG sample from a University-based clinic resemble those reported in other Brazilian series and in the international literature. |
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Associação Médica Brasileira |
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2015 |
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http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0104-42302015000200156 |
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