Clinical profile of patients with myasthenia gravis followed at the University Hospital, Federal University of Minas Gerais

Summary Objective: to determine the clinical profile of patients with myasthenia gravis (MG); followed at the Neuromuscular Diseases Clinic of the University Hospital, Federal University of Minas Gerais, Brazil, and to compare it with other Brazilian case series. Methods: sociodemographic and clinical data were collected from patients, and a systematic literature review performed, focusing on national studies on the clinical profile of MG patients. Results: sixty nine patients were enrolled in the study. Fifty five (91%) subjects were female and the mean age (SD) was 37.6 (±11.4) years. The mean disease duration was 14.1 years. Regarding treatment, prednisone was the most used strategy (64%), followed by the use of azathioprine (43%). There was no difference between thymectomized (42) and non-thymectomized (27) patients regarding disease severity and medication use. Conclusion: clinical and socio-demographic features of this MG sample from a University-based clinic resemble those reported in other Brazilian series and in the international literature.

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Bibliographic Details
Main Authors: Mourão,Aline Mansueto, Barbosa,Luiz Sérgio Mageste, Comini-Frota,Elizabeth Regina, Freitas,Denise da Silva, Gomez,Rodrigo Santiago, Burns,Ted M., Lemos,Stela Maris Aguiar, Teixeira,Antonio Lúcio
Format: Digital revista
Language:English
Published: Associação Médica Brasileira 2015
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0104-42302015000200156
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