Histopathological findings and detection of parasites in the eyes of dogs infected naturally with Leishmania chagasi

The objective of the present study was to investigate the histopathological alterations and detection of parasites that occur in the eyes of dogs naturally infected with Leishmania chagasi. The eyes of 25 dogs with a positive parasitological and serological exam for L. chagasi were submitted to routine ophthalmic examination. Fragments were obtained from the eyeball and were analyzed by immunohistochemistry and histopathology. Among the structures studied, the conjunctiva of the third eyelid was the tissue most frequently stained for L. chagasi. Histopathological analysis revealed a predominantly mononuclear inflammatory infiltrate whose intensity ranged from discrete to intense in the various ocular structures. Vascular congestion and perivasculitis were also observed. The histopathological alterations that occur in the eyeball of dogs with visceral leishmaniasis might be related to the presence of antibodies.

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Bibliographic Details
Main Authors: Brito,Fábio Luiz da Cunha, Laus,José Luiz, Tafuri,Wagner Luiz, Figueiredo,Maria Marta, Silva Júnior,Valdemiro Amaro, Maia,Frederico Celso Lyra, Alves,Leucio Câmara
Format: Digital revista
Language:English
Published: Universidade Federal de Santa Maria 2010
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782010000500022
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