Essential Oil from Flowers of Solanum stipulaceum: Composition, Effects of γ-Radiation, and Antileukemic Activity

The composition of essential oils from flowers of Solanum stipulaceum Roem & Schult collected in May and September was studied for the first time. Effects of g-radiation on volatile constituents were investigated by gas chromatography (GC) with flame ionization detector (FID). In addition, the antileukemic activity was studied by a 3-(4,5-dimethylthiazol-2-yl)-2,5- diphenyltetrazolium bromide (MTT) colorimetric assay against human cell lines HL-60 and THP-1. The main constituents of the essential oil of flowers collected in May were β-caryophyllene (25.8%), γ-gurjunene (11.9%), and β-gurjunene (8.2%), whereas the essential oil of flowers collected in September was mainly composed of β-caryophyllene (26.5%), caryophyllene oxide (11.0%), and γ-gurjunene (10.0%). The main components of essential oil from flowers collected in September were not significantly affected by γ-radiation at lower doses than 10.0 kGy. No cytotoxic activity in leukemic cell lines was observed for non-irradiated samples. However, irradiated samples exhibited slightly cytotoxic activity.

Bibliographic Details

Main Authors:	Osorio,Aura M. B., Silva,Thiago M., Duarte,Lucienir P., Ferraz,Vany P., Pereira,Márcio T., Mercadante-Simões,Maria O., Evangelista,Fernanda C. G., Sabino,Adriano P., Alcântara,Antônio F. C.
Format:	Digital revista
Language:	English
Published:	Sociedade Brasileira de Química 2015
Online Access:	http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532015001102233
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