Solid-phase synthesis of isoalloxazines using merrifield resin

The reaction of Merrifield resin bound diamino compounds with alloxan monohydrate gave 7-resin bound 10-substituted isoalloxazines that were characterized by solid phase fluorescence and IR spectroscopy. The resin was cleaved by 40% aqueous HF/DMF to give 7-carboxy-10-substituted isoalloxazines that were characterized by UV-vis., IR, ¹H NMR, fluorescence and elemental analysis.

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Bibliographic Details
Main Authors: Geetanjali, Singh,Ram, Chauhan,S.M.S
Format: Digital revista
Language:English
Published: Sociedade Brasileira de Química 2006
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532006000200030
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