Molecular epidemiology of dengue viruses in Brazil
Dengue viruses (DEN) are found as four antigenically distinct serotypes designated DEN-1, 2, 3, and 4. Laboratory evidence that strain-intratypical variation occurs among DEN viruses has been demonstrated since the 1970s, although only with the advances in molecular technologies has it been possible to determine the genetic variability of each serotype. Genotypical identification has proven to be a useful tool for determining the origin and spread of epidemics and to correlate virulence of strains. In this report we present the results of molecular epidemiological studies with the DEN-1 and DEN-2 viruses that caused dengue epidemics in Brazil during the last decade.
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| Main Authors: | , , |
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| Format: | Digital revista |
| Language: | English |
| Published: |
Escola Nacional de Saúde Pública Sergio Arouca, Fundação Oswaldo Cruz
2000
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| Online Access: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-311X2000000100021 |
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