Decreased expression of cardiac troponin C is associated with cardiac lesions in Amorimia exotropica poisoned cattle
The plants which cause sudden death of cattle in Brazil occupy a leading position for losses in the cattle industry. Amorimia exotropica is one of the plants pertaining to this group. Diagnostic findings in these cases may be inconclusive; further knowledge is necessary. This paper identifies cardiac lesions through anti-cardiac troponin C (cTnC) immunehistochemistry performed in tissues from cattle poisoned after consumption of A.exotropica in southern Brazil. Heart fragments from nine A. exotropica-poisoned cattle were studied immunohistochemically using anti-human cTnC as the primary antibody. In the hearts from all of the poisoned cattle, there was a sharp decrease in the cTnC expression level in the cytoplasm of groups of cardiomyocytes. A significant decrease in anti-cTnC immunoreactivity occurred particularly in degenerated or necrotic cardiomyocytes. Occasional groups of cells showed complete loss of immunolabeling. In the remaining intact cardiomyocytes from poisoned cattle and in cardiomyocytes from six cattle that died from other causes there was intense cytoplasmic staining.
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Colégio Brasileiro de Patologia Animal - CBPA
2012
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oai:scielo:S0100-736X20120010000102012-10-24Decreased expression of cardiac troponin C is associated with cardiac lesions in Amorimia exotropica poisoned cattlePavarini,Saulo PetinattiBandinelli,Marcele BettimJuffo,Gregory DuarteSouza,Suyene Oltramari deDriemeier,DavidCruz,Cláudio Estêvão Farias da Amorimia exotropica cattle sudden death troponin immunohistochemistry cardiac injury The plants which cause sudden death of cattle in Brazil occupy a leading position for losses in the cattle industry. Amorimia exotropica is one of the plants pertaining to this group. Diagnostic findings in these cases may be inconclusive; further knowledge is necessary. This paper identifies cardiac lesions through anti-cardiac troponin C (cTnC) immunehistochemistry performed in tissues from cattle poisoned after consumption of A.exotropica in southern Brazil. Heart fragments from nine A. exotropica-poisoned cattle were studied immunohistochemically using anti-human cTnC as the primary antibody. In the hearts from all of the poisoned cattle, there was a sharp decrease in the cTnC expression level in the cytoplasm of groups of cardiomyocytes. A significant decrease in anti-cTnC immunoreactivity occurred particularly in degenerated or necrotic cardiomyocytes. Occasional groups of cells showed complete loss of immunolabeling. In the remaining intact cardiomyocytes from poisoned cattle and in cardiomyocytes from six cattle that died from other causes there was intense cytoplasmic staining.info:eu-repo/semantics/openAccessColégio Brasileiro de Patologia Animal - CBPAPesquisa Veterinária Brasileira v.32 n.10 20122012-10-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-736X2012001000010en10.1590/S0100-736X2012001000010 |
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Pavarini,Saulo Petinatti Bandinelli,Marcele Bettim Juffo,Gregory Duarte Souza,Suyene Oltramari de Driemeier,David Cruz,Cláudio Estêvão Farias da |
| spellingShingle |
Pavarini,Saulo Petinatti Bandinelli,Marcele Bettim Juffo,Gregory Duarte Souza,Suyene Oltramari de Driemeier,David Cruz,Cláudio Estêvão Farias da Decreased expression of cardiac troponin C is associated with cardiac lesions in Amorimia exotropica poisoned cattle |
| author_facet |
Pavarini,Saulo Petinatti Bandinelli,Marcele Bettim Juffo,Gregory Duarte Souza,Suyene Oltramari de Driemeier,David Cruz,Cláudio Estêvão Farias da |
| author_sort |
Pavarini,Saulo Petinatti |
| title |
Decreased expression of cardiac troponin C is associated with cardiac lesions in Amorimia exotropica poisoned cattle |
| title_short |
Decreased expression of cardiac troponin C is associated with cardiac lesions in Amorimia exotropica poisoned cattle |
| title_full |
Decreased expression of cardiac troponin C is associated with cardiac lesions in Amorimia exotropica poisoned cattle |
| title_fullStr |
Decreased expression of cardiac troponin C is associated with cardiac lesions in Amorimia exotropica poisoned cattle |
| title_full_unstemmed |
Decreased expression of cardiac troponin C is associated with cardiac lesions in Amorimia exotropica poisoned cattle |
| title_sort |
decreased expression of cardiac troponin c is associated with cardiac lesions in amorimia exotropica poisoned cattle |
| description |
The plants which cause sudden death of cattle in Brazil occupy a leading position for losses in the cattle industry. Amorimia exotropica is one of the plants pertaining to this group. Diagnostic findings in these cases may be inconclusive; further knowledge is necessary. This paper identifies cardiac lesions through anti-cardiac troponin C (cTnC) immunehistochemistry performed in tissues from cattle poisoned after consumption of A.exotropica in southern Brazil. Heart fragments from nine A. exotropica-poisoned cattle were studied immunohistochemically using anti-human cTnC as the primary antibody. In the hearts from all of the poisoned cattle, there was a sharp decrease in the cTnC expression level in the cytoplasm of groups of cardiomyocytes. A significant decrease in anti-cTnC immunoreactivity occurred particularly in degenerated or necrotic cardiomyocytes. Occasional groups of cells showed complete loss of immunolabeling. In the remaining intact cardiomyocytes from poisoned cattle and in cardiomyocytes from six cattle that died from other causes there was intense cytoplasmic staining. |
| publisher |
Colégio Brasileiro de Patologia Animal - CBPA |
| publishDate |
2012 |
| url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-736X2012001000010 |
| work_keys_str_mv |
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| _version_ |
1756390039263117312 |