Evaluation of tests based on the antibody response to keyhole limpet haemocyanin and soluble egg antigen to differentiate acute and chronic human schistosomiasis mansoni

Evaluation of tests based on the antibody response to keyhole limpet haemocyanin and soluble egg antigen to differentiate acute and chronic human schistosomiasis mansoni

Specific IgG and IgM responses to soluble egg antigen (SEA) and keyhole limpet haemocyanin (KLH) were measured by ELISA in patients with acute and chronic schistosomiasis. The tests based upon IgM and IgG antibodies responses to KLH presented the best diagnostic discrimination, and can be used in conjunction with clinical and epidemiological data to the differential diagnosis of acute schistosomiasis.

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Bibliographic Details
Main Authors: Beck,Lílian, Van-Lüme,Daniele SM, Souza,Joelma R de, Morais,Clarice N Lins de, Melo,Wlademir G, Xavier,Edeneide, Barbosa,Constança S, Aroucha,Marcílio L, Domingues,Ana Lúcia C, Favre,Tereza, Pieri,Otávio, Abath,Frederico GC, Montenegro,Silvia ML
Format: Digital revista
Language:English
Published: Instituto Oswaldo Cruz, Ministério da Saúde 2004
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762004000900017
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