Trypanosoma cruzi: circulating antigens

Circulating antigens were detected in sera of mice experimentally infected with a high close of Trypanosoma cruzi by reaction with sera from chronically infected mice. The immunodiffusion reaction between homologous acute and chronic sera produced four precipitation lines. By reaction with chronic mouse serum, circulating antingens were detected in sera from heavily infected hamsters, dogs, rabbits and in sera from chagasic patients. A reaction was also found in urine from acutely infected mice and dogs. Trypanosoma cruzi exoantigen was detected in trypanosome culture medium and in the supernatant of infected cell cultures. Attempts to isolate the antigens are described.

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Bibliographic Details
Main Authors: Bongertz,V., Hungerer,Klaus-Dieter, Galvão-Castro,Bernardo
Format: Digital revista
Language:English
Published: Instituto Oswaldo Cruz, Ministério da Saúde 1981
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02761981000100008
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