Clinical Course After Cardioverter-Defibrillator Implantation: Chagasic Versus Ischemic Patients

Abstract Background: The outcome of Chagas disease patients after receiving implantable cardioverter defibrillator (ICD) is still controversial. Objective: To compare clinical outcomes after ICD implantation in patients with chronic Chagas cardiomyopathy (CCC) and ischemic heart disease (IHD). Methods: Prospective study of a population of 153 patients receiving ICD (65 with CCC and 88 with IHD). The devices were implanted between 2003 and 2011. Survival rates and event-free survival were compared. Results: The groups were similar regarding sex, functional class and ejection fraction. Ischemic patients were, on average, 10 years older than CCC patients (p < 0.05). Patients with CCC had lower schooling and monthly income than IHD patients (p < 0.05). The number of appropriate therapies was 2.07 higher in CCC patients, who had a greater incidence of appropriate shock (p < 0.05). Annual mortality rate and electrical storm incidence were similar in both groups. There was no sudden death in CCC patients, and only one in IHD patients. Neither survival time (p = 0.720) nor event-free survival (p = 0.143) significantly differed between the groups. Conclusion: CCC doubles the risk of receiving appropriate therapies as compared to IHD, showing the greater complexity of arrhythmias in Chagas patients.

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Bibliographic Details
Main Authors: Pereira,Francisca Tatiana Moreira, Rocha,Eduardo Arrais, Monteiro,Marcelo de Paula Martins, Lima,Neiberg de Alcantara, Rodrigues Sobrinho,Carlos Roberto Martins, Pires Neto,Roberto da Justa
Format: Digital revista
Language:English
Published: Sociedade Brasileira de Cardiologia - SBC 2016
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0066-782X2016004100099
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