Clinical and laboratorial features of oral candidiasis in HIV-positive patients

Abstract INTRODUCTION We describe the clinical and laboratorial features of oral candidiasis in 66 HIV-positive patients. METHODS: Polymerase chain reaction-based techniques were performed for differentiation of Candida spp. isolated from patients at a public teaching hospital in Midwest Brazil. RESULTS: Oral lesions, mainly pseudomembranous, were significantly related to higher levels of immunosuppression. Of 45 Candida isolates, 66.7% were C. albicans. Most of the isolates were susceptible to the antifungal drugs tested. CONCLUSIONS: Oral lesions were associated with higher immunosuppression levels. Lower susceptibility to antifungals by non-albicans isolates supports the importance of surveillance studies using susceptibility tests to aid in the treatment.

Bibliographic Details

Main Authors:	Spalanzani,Regiane Nogueira, Mattos,Karine, Marques,Luiza Inahe, Barros,Pedro Fernando Diniz, Pereira,Pamela Iruama Peres, Paniago,Anamaria Mello Miranda, Mendes,Rinaldo Poncio, Chang,Marilene Rodrigues
Format:	Digital revista
Language:	English
Published:	Sociedade Brasileira de Medicina Tropical - SBMT 2018
Online Access:	http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822018000300352
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