SILVER NANOPARTICLES-DISK DIFFUSION TEST AGAINST Escherichia coli ISOLATES

SUMMARY Nanotechnology can be a valuable ally in the treatment of infections. Silver nanoparticles (AgNPs) are structures that have antimicrobial activity. The aim of this study was to produce AgNPs by green methods, characterize these structures, and assess their antimicrobial activity against Escherichia coli associated with the antibiotic ciprofloxacin. AgNPs were characterized by spectroscopic and microscopic techniques. Antimicrobial activity was evaluated by the disk diffusion method against 10 strains of E. coli. The synthesized AgNPs showed a spherical shape and a size of 85.07 ± 12.86 nm (mean ± SD). AgNPs increased the activity of ciprofloxacin by 40% and may represent a new therapeutic option for the treatment of bacterial infections.

Bibliographic Details

Main Authors:	CUNHA,Francisco Afrânio, MAIA,Kamila Rocha, MALLMAN,Eduardo José Jucá, CUNHA,Maria da Conceição dos Santos Oliveira, MACIEL,Antonio Auberson Martins, SOUZA,Ieda Pereira de, MENEZES,Everardo Albuquerque, FECHINE,Pierre Basílio Almeida
Format:	Digital revista
Language:	English
Published:	Instituto de Medicina Tropical de São Paulo 2016
Online Access:	http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0036-46652016005000505
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