Epidemiological survey of Trypanosoma cruzi infection in North-Eastern Brazil using different diagnostic methods

A survey of the prevalence of Trypanosoma cruzi infection was carried out in Oitis, a small community in the State of Piaui, Brazil. Two hundred and sixty five individuals were screened by microscopic examination, hémoculture, indirect immunofluorescence (IFA), enzyme-linked immunosorbent assay (ELISA), and competitive enzyme-linked immunosorbent assay (C-ELISA) using the monoclonal antibody TCF87 against to a 25kd T. cruzi antigen. Seropositivity was 14.3% by the IFA test, 14.7% by ELISA, and 13.2% by C-ELISA. The C-ELISA using the TCF87 monoclonal antibody seems to be applicable in serodiagnosis of Chagas' disease.

Bibliographic Details

Main Authors:	Figuerêdo-Silva,José, Kaneda,Yoshimasa, Tachibana,Hiroshi, Furushima,Rieko, Tateno,Seiki, Correia-Lima,Fernando Gomes, Bento,Dalva Neves da Costa
Format:	Digital revista
Language:	English
Published:	Instituto de Medicina Tropical de São Paulo 1991
Online Access:	http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0036-46651991000300005
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