Fascioliasis hepática humana: resistencia al tratamiento con triclabendazol

Human fascioliasis is a parasitic zoonosis that affects the liver of human and herbivorous animals. In chronic cases, its diagnosis is confirmed by direct visualization of parasitic eggs in stool examination, by positive testing for Fasciola hepatica antigens in stools, or by direct observation of parasites by endoscopic retrograde cholangiography or surgery. In acute cases, serological reactions as immunoblothing or detection of parasite antigens in the blood are useful. The treatment of choice is triclabendazole. However, parasite resistance in animals, as well as in man, has been reported to this drug. We report four patients in whom the parasitic infection persisted despite a course of treatment with triclabendazole.

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Bibliographic Details
Main Authors: Gil,Luis Carlos, Díaz,Alex, Rueda,Carlos, Martínez,Christian, Castillo,Douglas, Apt,Werner
Format: Digital revista
Language:Spanish / Castilian
Published: Sociedad Médica de Santiago 2014
Online Access:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872014001000014
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