Neuro-Behçet: differential diagnosis of recurrent meningitis

Behçet disease is a systemic inflammatory perivasculitis characterized by recurrent episodes oforal and genital ulcers associated with skin and ocular lesions. Neurological involvement occurs in 5 to 10% of the cases, and isolated meningeal involvement is very uncommon. We report a 21 years old man with a Behçet disease and a history of acute meningeal syndrome in two previous crises and meningoencephalitis in three others. He reported a history of conjunctivitis and oral and genital ulcers. On examination, he presented oral aphthoid lesions, macular edema, involvement of cranial nerves, pyramidal signs and meningeal irritation. The cell count in cerebrospinal fluid was 1800 cells/mm³, with polymorphonuclear predominance. Magnetic resonance imaging showed lesions in basal ganglia and the brainstem. The patient improved dramatically after intravenous steroid therapy.

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Bibliographic Details
Main Authors: Fonseca Cardoso,Andreya, Rocha-Filho,Pedro Augusto, Melo Correa-Lima,Ana Rosa
Format: Digital revista
Language:English
Published: Sociedad Médica de Santiago 2013
Online Access:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872013000100016
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