Hipotermia intravascular inducida en el manejo de la hipertensión intracraneana en insuficiencia hepática aguda: Caso clínico

Acute liver failure has a mortality rate in excess of 80%. Most deaths are attributed to brain edema with intracranial hypertension and herniation of structures, where ammonium plays a major role in its generation. We report an 18 year-old female with a fulminant hepatic failure caused by virus A infection. The patient developed a profound sopor and required mechanical ventilation. A CT scan showed the presence of brain edema and intracranial hypertension. A Raudemic® catheter was inserted to measure intracranial pressure and brain temperature. Intracranial hypertension became refractory and intravascular hypothermia was started, reducing brain temperature to 33°C. Seventy two hours later, a liver transplantation was performed. After testing graft perfusion, rewarming was started, completing 122 hours of hypothermia at 33°C. The patient was discharged in good conditions after 69 days of hospitalization.

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Detalhes bibliográficos
Principais autores: Castillo F,Luis, Pérez R,Cristian, Ruiz B,Carolina, Bugedo T,Guillermo, Hernández P,Glenn, Martínez C,Jorge, Jarufe C,Nicolás, Pérez A,Rosa, Mellado T,Patricio, Domínguez,Pilar
Formato: Digital revista
Idioma:Spanish / Castilian
Publicado em: Sociedad Médica de Santiago 2009
Acesso em linha:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872009000600010
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