Embriopatía por isotretinoína: Un daño evitable

Retinoic acid is a widely used drug in the treatment of cystic acné. It has teratogenic effects that depend on the gestational period in which it is used. We report a seven months of female whose mother was exposed to retinoic acid in both pregestational and gestational periods. She had a retardation of psychomotor development and a brain MRI showed frontal atrophy and a malformation of the posterior fossa. We discuss the mechanisms ofthe teratogenic effeets of retinoic acid

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Bibliographic Details
Main Authors: Troncoso Sen,Mónica, Rojas H,Carla, Bravo C,Eduardo
Format: Digital revista
Language:Spanish / Castilian
Published: Sociedad Médica de Santiago 2008
Online Access:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872008000600012
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