Urinary dysfunction with detrusor hyperactivity in women with Parkinson's disease cannot be blamed as a factor of worsening motor performance

Introduction Detrusor hyperactivity is the leading cause of urinary dysfunction in Parkinson's disease (PD). There are few studies correlating PD clinical aspects with this autonomic feature. Methods A cohort of 63 women with PD were prospectively examined for assessment of clinical aspects and disease severity using unified Parkinson's disease rating scale and Hoehn-Yahr scale, respectively. The urologic function was evaluated by the urodynamic study. Two groups were categorized at this time - groups with and without detrusor hyperactivity. After seven years, the same parameters were re-evaluated. Results Progression of the disease on mental scores was found in the group with detrusor hyperactivity. On follow-up, clinical symptoms and severity did not show significant worsening between the groups. Conclusion Detrusor hyperactivity is a frequent urodynamic finding in PD, and even though it is associated with dopaminergic dysfunction, it cannot be blamed as a factor of worsening motor performance, but is probably associated with poor cognitive and mental prognosis.

Bibliographic Details

Main Authors:	Campos-Sousa,Raimundo Nonato, Quagliato,Elizabeth Maria Aparecida Barasnevicius, Almeida,Kelson James, Castro,Inacio Augusto Dias de, Campelo,Viriato
Format:	Digital revista
Language:	English
Published:	Academia Brasileira de Neurologia - ABNEURO 2013
Online Access:	http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2013000900591
Tags:	Add Tag No Tags, Be the first to tag this record!