CSF markers for diagnosis of bacterial meningitis in neurosurgical postoperative patients

OBJECTIVE: To evaluate the diagnostic usefulness of cerebral spinal fluid (CSF) cellularity, protein, neutrophils, glucose and lactate for detection of postoperative bacterial meningitis. METHOD: This prospective study was conducted in 28 postoperative neurosurgical patients from 2002 to 2005 at University of São Paulo. The CSF markers were plotted in a receiver operating characteristic (ROC) curve to evaluate their accuracy. RESULTS: Based on the area under ROC curve CSF glucose, cellularity, and lactate were considered good tests. Polymorphonuclear and protein did not achieve enough accuracy to be used clinically. CONCLUSION: The CSF glucose, lactate, and cellularity can be used for the diagnosis of bacterial meningitis. Moreover, it can be helpful to differentiate bacterial from aseptic meningitis.

Bibliographic Details

Main Authors:	Tavares,Wagner Malagó, Machado,Andre Guelman, Matushita,Hamilton, Plese,Jose Pindaro P.
Format:	Digital revista
Language:	English
Published:	Academia Brasileira de Neurologia - ABNEURO 2006
Online Access:	http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2006000400012
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