Central neurocytoma: report of two cases

INTRODUCTION: Central neurocytomas are rare neuroectodermal tumors believed to arise from the subependymal matrix of the lateral ventricles. CASE REPORTS: A 26-year-old woman and a 33-year-old man each had a large, heterogeneous, contrast enhancing mass in the lateral ventricles at the foramen of Monro causing bilateral hydrocephalus. The woman died after surgery, but the man is asymptomatic after three years. HISTOPATHOLOGY: Both tumors were composed of isomorphic rounded cells positive for synaptophysin, chromogranin and NSE, while some reacted for GFAP, vimentin and S-100 protein. Electron microscopy revealed neuropil-like tissue between cells, but synapses were rare.

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Bibliographic Details
Main Authors: Borges,Guilherme, Pereira,Hoyama Costa, Carelli,Edmur Franco, Fernandes,Yvens Barbosa, Bonilha,Leonardo, Roma,Maria Fernanda, Zanardi,Verônica A., Menezes Netto,José R., Schenka,André A., Queiroz,Luciano S.
Format: Digital revista
Language:English
Published: Academia Brasileira de Neurologia - ABNEURO 2005
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2005000600031
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