Genetic predisposition to febrile convulsions: a preliminary study

The participation of genetic factors in the origin of convulsive disorders is a controversial matter. In an attempt to study the influence of heredity in a selected group of patients, we evaluated 128 subjects that presented febrile febrile convulsions. Of these, 18 (14,3 % of the sample) had at least one relative affected by the same problem. Even though a more definite conclusion depends on sample enlargement and on setting up a control group, pedigree observation suggests the participation of an autosomal dominant gene, with incomplete and probably low penetrance, in the etiology of febrile convulsions.

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Bibliographic Details
Main Authors: Raffin,Cesar Noronha, Giuoliani,Roberto, Armbrust-Fgueiredo,Jorge
Format: Digital revista
Language:English
Published: Academia Brasileira de Neurologia - ABNEURO 1980
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X1980000400001
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