Intraocular pressure in schizophrenic patients treated with psychiatric medications

PURPOSE: In order to assess the occurrence of adverse ocular effects of antipsychotic drugs, we sought to evaluate intraocular pressure of schizophrenic patients treated with psychiatric medications. METHODS: Twenty-eight outpatients with DSM-IV diagnosis of schizophrenia who met both the inclusion and exclusion criteria were submitted to an ophthalmic evaluation for ocular abnormalities which included intraocular pressure measurement with Goldmann applanation tonometry. RESULTS: Raised intraocular pressure was found in three patients (11%). Abnormality in cup-disc ratio was seen in only one patient with cup-disc ratio asymmetry of 0.4. All these four patients were taking only ziprasidone. CONCLUSIONS: Patients using ziprasidone were found to have abnormalities in both intraocular pressure and cup-disc ratio.

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Bibliographic Details
Main Authors: Souza,Valéria Barreto Novais e, Moura Filho,Francisco José Rodrigues de, Souza,Fábio Gomes de Matos e, Pereira Filho,Sergio Augusto Carvalho, Coelho,Suele Serra, Furtado,Fernando Antônio Mendes Lopes, Gonçalves,Tiago Bessa Almeida, Vasconcelos,Karla Feitosa Ximenes
Format: Digital revista
Language:English
Published: Conselho Brasileiro de Oftalmologia 2008
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-27492008000500009
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