Late-onset persistent retinal microvascular changes after bone marrow transplantation: 3-year follow-up

Purpose: To describe a case of persistent retinopathy after bone marrow transplantation in the absence of radiation therapy. Methods: Case Report. Results: A 42 year-old man developed bilateral visual loss 15 months after receiving a bone marrow transplant for acute leukemia. The patient was treated with a high dose of cyclosporin A and oral corticosteroids. No radiation therapy was given. Late-onset, multiple, bilateral cotton-wool spots developed 15 months after the bone marrow transplantation and still persist. After three years other cotton-wool spots arose in the absence of any immunosuppressive therapy. Conclusions: Bone marrow transplantation microvasculopathy of the retina may be related to certain combinations of chemotherapy drugs or immunosuppression itself and may persist in the absence of these immunosuppressive drugs.

Bibliographic Details

Main Authors:	Muccioli,Cristina, Belfort Jr,Rubens, Jorge,Rodrigo, Farah,Michel Eid, Pereira,Mauricio B.
Format:	Digital revista
Language:	English
Published:	Conselho Brasileiro de Oftalmologia 2002
Online Access:	http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-27492002000300017
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