Meningoencephalitis caused by Mycobacterium bovis in a calf. Case report

A clinical case of tuberculous meningoencephalitis in a 5-month-old Holstein calf that presented nervous symptoms is described. The calf was part of a herd with a 30% prevalence of tuberculosis. The animal was euthanized, and a necropsy was performed. No lesions were found in organs of the thoracic or abdominal cavity. Brain samples were taken for histopathology (hematoxylin-eosin and Zielh Nelsen staining), bacteriology and PCR-MRD1 studies. In the brain, macroscopic inflammatory lesions with congestion and granular appearance were observed in the meninges, as well as fibrous adhesions in the ventral area. Microscopically, inflammatory infiltrate, lymphocytes, macrophages, epithelioid cells, plasma cells and multinucleated giant cells, areas of central necrosis, dystrophic mineralization and acid-fast bacilli were observed. Granulomatous meningoencephalitis due to Mycobacterium bovis was confirmed by bacterial isolation and PCR-MRD1.

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Bibliographic Details
Main Authors: Favila-Humara, Lucia del Carmen, Santillán-Flores, Marco Antonio, Martínez-Serrano, María Guadalupe, Morales-Álvarez, José Francisco
Format: Digital revista
Language:spa
Published: Universidad Nacional Mayor de San Marcos, Facultad de Medicina Veterinaria 2021
Online Access:https://revistasinvestigacion.unmsm.edu.pe/index.php/veterinaria/article/view/19498
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