Phylogenetic and structural analyses of equine rotaviruses : three possible geographically related lineages
The structural analyses revealed that the aa substitutions in VP7 are in the antigenic sites and in the VP7:VP6 interaction region. In accordance, most of the aa changes in VP6 are in the top of the protein involving antigenic and VP7:VP6 interaction sites. Interestingly, the structural analyses of VP8* showed a few aa differences in the antigenic sites and, all equine P[12] shown the same conserved aa sequence in VP8* pocket, only observed in P[12] genotype. Our study suggest the existence of geographically related equine RVA lineages and, describe the aa configuration of the VP8* pocket.
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| Auteurs principaux: | , , |
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| Format: | info:eu-repo/semantics/article biblioteca |
| Langue: | eng |
| Publié: |
2016
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| Sujets: | Animal Diseases, Horses, Genetics, Enfermedades de los Animales, Rotavirus, Caballos, Genética, |
| Accès en ligne: | http://hdl.handle.net/20.500.12123/1015 http://www.j-evs.com/article/S0737-0806(16)00086-1/pdf http://dx.doi.org/10.1016/j.jevs.2016.02.055 |
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