Effect of finishing period length with α-tocopherol supplementation on the expression of vitamin E-related genes in the muscle and subcutaneous fat of light lambs
The aim of this study was to investigate how different finishing period lengths with α-tocopherol supplementation or alfalfa grazing affect mRNA expression levels of genes related to vitamin E metabolism in L. thoracis (LT) muscle and subcutaneous fat (SF) from lambs of the Rasa Aragonesa breed. Indoors, concentrate-fed light lambs (n. =. 48) were supplemented with 500. dl-α-tocopheryl acetate/kg concentrate for an average finishing period length of 0 (C), 10.7 (VE10d), 21.2 (VE20d) and, 32.3 (VE30d) days before slaughtering. Simultaneously, 8 lambs with their dams were alfalfa-grazed. The α-tocopherol affected in a short-term the expression of genes in LT muscle (. ABCA1, LPL, APOE, and SREBP1) and SF (. ABCA1, SCARB1, LPL, and PPARG). On the contrary, PPARA gene expression showed a long-term α-tocopherol effect because the highest levels of PPARA mRNA were found in the VE30d. © 2014 Elsevier B.V.
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dig-inia-es-20.500.12792-19252020-12-15T09:46:44Z Effect of finishing period length with α-tocopherol supplementation on the expression of vitamin E-related genes in the muscle and subcutaneous fat of light lambs González-Calvo, L. Joy, M. Alberti, C. Ripoll, G. Molino, F. Serrano, M. Calvo, J. H. The aim of this study was to investigate how different finishing period lengths with α-tocopherol supplementation or alfalfa grazing affect mRNA expression levels of genes related to vitamin E metabolism in L. thoracis (LT) muscle and subcutaneous fat (SF) from lambs of the Rasa Aragonesa breed. Indoors, concentrate-fed light lambs (n. =. 48) were supplemented with 500. dl-α-tocopheryl acetate/kg concentrate for an average finishing period length of 0 (C), 10.7 (VE10d), 21.2 (VE20d) and, 32.3 (VE30d) days before slaughtering. Simultaneously, 8 lambs with their dams were alfalfa-grazed. The α-tocopherol affected in a short-term the expression of genes in LT muscle (. ABCA1, LPL, APOE, and SREBP1) and SF (. ABCA1, SCARB1, LPL, and PPARG). On the contrary, PPARA gene expression showed a long-term α-tocopherol effect because the highest levels of PPARA mRNA were found in the VE30d. © 2014 Elsevier B.V. 2020-10-22T12:21:02Z 2020-10-22T12:21:02Z 2014 journal article http://hdl.handle.net/20.500.12792/1925 10.1016/j.gene.2014.09.037 eng Attribution-NonCommercial-ShareAlike 4.0 International http://creativecommons.org/licenses/by-nc-sa/4.0/ open access |
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The aim of this study was to investigate how different finishing period lengths with α-tocopherol supplementation or alfalfa grazing affect mRNA expression levels of genes related to vitamin E metabolism in L. thoracis (LT) muscle and subcutaneous fat (SF) from lambs of the Rasa Aragonesa breed. Indoors, concentrate-fed light lambs (n. =. 48) were supplemented with 500. dl-α-tocopheryl acetate/kg concentrate for an average finishing period length of 0 (C), 10.7 (VE10d), 21.2 (VE20d) and, 32.3 (VE30d) days before slaughtering. Simultaneously, 8 lambs with their dams were alfalfa-grazed. The α-tocopherol affected in a short-term the expression of genes in LT muscle (. ABCA1, LPL, APOE, and SREBP1) and SF (. ABCA1, SCARB1, LPL, and PPARG). On the contrary, PPARA gene expression showed a long-term α-tocopherol effect because the highest levels of PPARA mRNA were found in the VE30d. © 2014 Elsevier B.V. |
| format |
journal article |
| author |
González-Calvo, L. Joy, M. Alberti, C. Ripoll, G. Molino, F. Serrano, M. Calvo, J. H. |
| spellingShingle |
González-Calvo, L. Joy, M. Alberti, C. Ripoll, G. Molino, F. Serrano, M. Calvo, J. H. Effect of finishing period length with α-tocopherol supplementation on the expression of vitamin E-related genes in the muscle and subcutaneous fat of light lambs |
| author_facet |
González-Calvo, L. Joy, M. Alberti, C. Ripoll, G. Molino, F. Serrano, M. Calvo, J. H. |
| author_sort |
González-Calvo, L. |
| title |
Effect of finishing period length with α-tocopherol supplementation on the expression of vitamin E-related genes in the muscle and subcutaneous fat of light lambs |
| title_short |
Effect of finishing period length with α-tocopherol supplementation on the expression of vitamin E-related genes in the muscle and subcutaneous fat of light lambs |
| title_full |
Effect of finishing period length with α-tocopherol supplementation on the expression of vitamin E-related genes in the muscle and subcutaneous fat of light lambs |
| title_fullStr |
Effect of finishing period length with α-tocopherol supplementation on the expression of vitamin E-related genes in the muscle and subcutaneous fat of light lambs |
| title_full_unstemmed |
Effect of finishing period length with α-tocopherol supplementation on the expression of vitamin E-related genes in the muscle and subcutaneous fat of light lambs |
| title_sort |
effect of finishing period length with α-tocopherol supplementation on the expression of vitamin e-related genes in the muscle and subcutaneous fat of light lambs |
| publishDate |
2014 |
| url |
http://hdl.handle.net/20.500.12792/1925 |
| work_keys_str_mv |
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1758005103474769920 |