Effect of finishing period length with α-tocopherol supplementation on the expression of vitamin E-related genes in the muscle and subcutaneous fat of light lambs

The aim of this study was to investigate how different finishing period lengths with α-tocopherol supplementation or alfalfa grazing affect mRNA expression levels of genes related to vitamin E metabolism in L. thoracis (LT) muscle and subcutaneous fat (SF) from lambs of the Rasa Aragonesa breed. Indoors, concentrate-fed light lambs (n. =. 48) were supplemented with 500. dl-α-tocopheryl acetate/kg concentrate for an average finishing period length of 0 (C), 10.7 (VE10d), 21.2 (VE20d) and, 32.3 (VE30d) days before slaughtering. Simultaneously, 8 lambs with their dams were alfalfa-grazed. The α-tocopherol affected in a short-term the expression of genes in LT muscle (. ABCA1, LPL, APOE, and SREBP1) and SF (. ABCA1, SCARB1, LPL, and PPARG). On the contrary, PPARA gene expression showed a long-term α-tocopherol effect because the highest levels of PPARA mRNA were found in the VE30d. © 2014 Elsevier B.V.

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Bibliographic Details
Main Authors: González-Calvo, L., Joy, M., Alberti, C., Ripoll, G., Molino, F., Serrano, M., Calvo, J. H.
Format: journal article biblioteca
Language:eng
Published: 2014
Online Access:http://hdl.handle.net/20.500.12792/1925
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