African swine fever and classical swine fever A review of the pathogenesis

African swine fever and classical swine fever A review of the pathogenesis

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This paper describes major pathogenetic mechanisms of African and Classical Swine Fever virus infections. The interactions between both viruses and the monocyte-macrophage-system result in the release of mediator molecules, which are important for the further progression of the diseases. The causes of the thrombocytopenia and the mechanisms of the haemorrhages, which are characteristic in both infections, are described. Apoptotic cell death is regarded as the pre-dominant cause of lymphopenia in both virus infections.

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Main Authors: Gómez-Villamandos, J. C., Carrasco, L., Bautista, M. J., Sierra, M. A., Quezada, M., Hervas, J., Chacón M. De Lara, F., Ruiz-Villamor, E., Salguero, F. J., Sánchez-Cordón, P. J., Romanini, S., Núñez, A., Mekonen, T., Méndez, A., Jover, A.
Format: artículo de revisión biblioteca
Language:English
Published: M. & H. Schaper GmbH 2003
Subjects:African swine fever, Classical swine fever, Monocyte-macrophage-system, Thrombocytopenia, Haemorrhages, Lymphopenia,
Online Access:http://hdl.handle.net/20.500.12792/1823
http://hdl.handle.net/10261/291796
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http://hdl.handle.net/20.500.12792/1823
http://hdl.handle.net/10261/291796

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