The effect of modification of hydroxy group of alkanol and benzyl alcohol to hydroxyalkyloxy group on nematicidal activity against pine wood nematode
Pine wood nematode (PWN), Bursaphelenchus xylophilus causes devastating damage to pines worldwide. Control and prevention of pine wood disease (PWD) in Korea is primarily trunk injection of abamectin and emamectin benzoate. Previously we found the nematicidal activity of 2-(1-undecyloxy)-1-ethanol (monochamol), which is reported to be aggregation pheromone of its vectors, Monochamus species, was as same to that of abamectin. Since then, we tried to develop new agent for controlling and preventing PWD using alkyloxyalkanols (ROR’OH) and benzyloxyalkanols (BzOROH). We synthesized ROR’OH and BzOROH by substituting hydroxy group (–OH) to hydroxyalkyloxy group (–OROH) and tested their nematicidal activity against PWN. As controls, monochamol and abamectin were also tested. The substitution –OH group to –OROH affected the nematicidal activity increasingly. The nematicidal activity was different according to total carbon chain length in compounds, although the compounds have same molecular formula. It may be due to the different position of oxy group in the compound of alkyloxyalkanol LC50 values of C10OC4OH, C6OC8OH, C10OC2OH and C12OC2OH were as same as that of monochamol. Substitution of hydroxy group of benzyl alcohol enhanced the nematicidal activity of new compound. Here, we will report the nematicidal activity changes by substitution –OH of alkanol and benzyl alcohol to –OROH. Keywords: Agriculture, Research ID: 3619465
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| Format: | Document biblioteca |
| Language: | English |
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FAO ;
2022
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| Online Access: | https://openknowledge.fao.org/handle/20.500.14283/CC4423EN http://www.fao.org/3/cc4423en/cc4423en.pdf |
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